Fundamental Principles
Treat patients based on clinical suspicion as soon as possible, preferably within the first 5 days of symptoms. Perform PCR testing, but do not withhold treatment pending results.
Risk Stratify Patients
Low Risk Patients: Younger than 45, no comorbidities, and clinically stable
High Risk Patients: Older than 45, younger than 45 with comorbidities, or clinically unstable
Treatment Options
Low Risk Patients
- Supportive care with fluids, fever control, and rest
- Elemental Zinc 50mg once a day for 7 days
- Vitamin C 1000mg once a day for 7 days
- Vitamin D3 5000iu once a day for 7 days
Over the counter options:
- Quercetin 500mg twice a day for 7 days or Epigallocatechin-gallate (EGCG) 400mg once a day for 7 days
Moderate / High Risk Patients
- Elemental Zinc 50-100mg once a day for 7 days
- Vitamin C 1000mg once a day for 7 days
- Vitamin D3 10000iu once a day for 7 days or 50000iu once a day for 1-2 days
- Azithromycin 500mg once a day for 5 days or Doxycycline 100mg twice a day for 7 days
- Hydroxychloroquine (HCQ) 200mg twice a day for 5-7 days and/or
- Ivermectin (IVM) 0.4-0.5mg/kg/day for 5-7 days
Either or both HCQ and IVM can be used, and if one only is used, the second agent can be added after about 2 days of treatment if obvious recovery has not yet been observed etc.
Treatment Options
- Dexamethasone 6-12mg once a day for 7 days or Prednisone 20mg twice a day for 7 days, taper as needed
- Budesonide 1mg/2cc solution via nebulizer twice a day for 7 days
- Blood thinners (i.e. Lovenox, Eliquis, Xarelto, Pradaxa, Aspirin)
- Colchicine 0.6mg 2-3 times a day for 5-7 days
- Monoclonal antibodies
- Home IV fluids and oxygen
